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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
J Biol Chem. 1999;274(20):14006-11.
A mutated PtsG, the glucose transporter, allows uptake of D-ribose.
Oh H, Park Y, Park C.
(
10318813
)
|
|
|
Deletion
|
OCR01-1
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
rbsK
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Related strains
|
|
Strains Search
|
Search strains by gene name:
rbsK
Search strains by all related name:
rbsK b3752 ECK3746 JW3731 o309 rbsP
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General information (Go to Linear View: )
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Gene Name
|
rbsK
|
|
Alternative name
|
b3752,ECK3746,JW3731,o309,rbsP
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|
Location, Length
|
3,935,317 - 3,936,246
(
+
)
;
84.82
min
;
930
(bp) ,
309
(aa)
|
|
Product
|
ribokinase
|
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Operon Name
|
rbsDACBKR
|
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Note
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GO_component: GO:0005737 - cytoplasm; GO_process: GO:0016052 - carbohydrate catabolic process
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Function
|
enzyme; Degradation of small molecules: Carbon compounds
|
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Gene Ontology
|
GO:0004747
;
ribokinase activity ( rbsK )
GO:0005515
;
protein binding ( rbsK )
GO:0005737
;
cytoplasm ( rbsK )
GO:0005975
;
carbohydrate metabolic process ( rbsK )
GO:0006014
;
D-ribose metabolic process ( rbsK )
GO:0016301
;
kinase activity ( rbsK )
GO:0016740
;
transferase activity ( rbsK )
|
|
PID
|
1790193
|
EC number
(KEGG Pathway)
|
2.7.1.15
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
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EcoGene
|
rbsK
(
EG10818
)
|
|
Number of removed
|
0 aa cleaved
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
RBSB_ECOLI
(
P02925
)
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- Protein name
|
D-ribose-binding periplasmic protein precursor.
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- Synonyms
|
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- Gene name
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Name=rbsB; Synonyms=rbsP, prlB; OrderedLocusNames=b3751;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
|
rbsK
(
homologous genes of other bacterias
)
|
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PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain , E. Coli Ribokinase Complexed With Ribose And Adp
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Ribokinase
|
|
PSI-BLAST
|
Bifunctional protein hldE [Includes: D-beta-D-heptose 7-phosphate kinase
|
|
nr
(database updated :
2007.02.20
)
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BLAST
|
ribokinase [Escherichia coli O157:H7 EDL933]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
|
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PROSITE
|
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PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
CYTOCHROME_C
PFKB_KINASES_1
PFKB_KINASES_2
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MMBR References
|
J Biol Chem. 1986;261:7663-7668
Ribokinase from Escherichia coli K12. Nucleotide sequence and overexpression of the rbsK gene and purification of ribokinase.
Hope, J. N., A. W. Bell, M. A. Hermodson, and J. M. Groarke.
|
J Bacteriol. 1984;158(2):674-82.
Molecular cloning and characterization of genes required for ribose transport and utilization in Escherichia coli K-12.
Iida A, Harayama S, Iino T, Hazelbauer GL.
(
6327617
)
|
J Bacteriol. 1984;158(2):665-73.
D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport.
Lopilato JE, Garwin JL, Emr SD, Silhavy TJ, Beckwith JR.
(
6327616
)
|
ICN-UCLA Symp. Mol. Cell. Biol. 1980;19:137-159.
The origin of replication, oriC, of the Escherichia coli chromosome: genes near oriC and construction of oriC deletion mutations.
von Meyenburg, K., F. G. Hansen, E. Riise, H. E. N. Bergmans, M. Meijer, and W. Messer.
|
| Sequences |
Amino acid
FASTA format
|
0001 MQNAGSLVVL GSINADHILN LQSFPTPGET VTGNHYQVAF GGKGANQAVA AGRSGANIAF IACTGDDSIG
0071 ESVRQQLATD NIDITPVSVI KGESTGVALI FVNGEGENVI GIHAGANAAL SPALVEAQRE RIANASALLM
0141 QLESPLESVM AAAKIAHQNK TIVALNPAPA RELPDELLAL VDIITPNETE AEKLTGIRVE NDEDAAKAAQ
0211 VLHEKGIRTV LITLGSRGVW ASVNGEGQRV PGFRVQAVDT IAAGDTFNGA LITALLEEKP LPEAIRFAHA
0281 AAAIAVTRKG AQPSVPWREE IDAFLDRQR
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GGTGACATAA ATACGTCATC GACAGATGAA
-070 CGTGTAATAT AAAGAAAAGC AGGGCACGCG CCACCCTAAC ACGGTGGCGC ATTTTATGGA CATCCCGAAT
0001 atgcaaaacg caggcagcct cgttgttctt ggcagcatta atgctgacca cattcttaat cttcaatctt
0071 ttcctactcc aggcgaaacc gtaaccggta accactatca ggttgcattt ggcggcaaag gcgcgaatca
0141 ggctgtggct gctgggcgta gcggtgcgaa tatcgcgttt attgcctgta cgggtgatga cagcattggt
0211 gagagcgttc gccagcagct cgccactgat aacattgata ttactccggt cagcgtgatc aaaggcgaat
0281 caacaggtgt ggcgctgatt tttgttaatg gcgaaggtga gaatgtcatc ggtattcatg ccggcgctaa
0351 tgctgccctt tccccggcgc tggtggaagc gcaacgtgag cgtattgcca acgcgtcagc attattaatg
0421 cagctggaat caccactcga aagtgtgatg gcagcggcga aaatcgccca tcaaaataag actatcgttg
0491 cgcttaaccc ggctccggct cgcgaacttc ctgacgaact gctggcgctg gtggacatta ttacgccaaa
0561 cgaaacggaa gcagaaaagc tcaccggtat tcgtgttgaa aatgatgaag atgcagcgaa ggcggcgcag
0631 gtactgcatg aaaaaggtat ccgtactgta ctgattactt taggaagtcg tggtgtatgg gctagcgtga
0701 atggtgaagg tcagcgcgtt cctggattcc gggtgcaggc tgtcgatacc attgctgccg gagatacctt
0771 taacggtgcg ttaatcacgg cattgctgga agaaaaacca ttgccagagg cgattcgttt tgcccatgct
0841 gccgctgcga ttgccgtaac acgtaaaggc gcacaacctt ccgtaccgtg gcgtgaagag atcgacgcat
0911 ttttagacag gcagaggtga CGCTTGGCTA CAATGAAAGA TGTTGCCCGC CTGGCGGGCG TTTCTACCTC
0981 AACAGTTTCT CACGTTATCA ATAAAGATCG CTTCGTCAGT GAAGCGATTA
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