|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
essential
|
|
References (PMID)
|
J Bacteriol. 1999;181(9):2733-8.
The Escherichia coli homologue of yeast RER2, a key enzyme of dolichol synthesis, is essential for carrier lipid formation in bacterial cell wall synthesis.
Kato J, Fujisaki S, Nakajima K, Nishimura Y, Sato M, Nakano A.
(
10217761
)
|
|
|
Deletion
|
OCR33,34-2
(D)
,
OCR33,35-4 (AK4-2 / BK5-2)
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
ispU
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
ispU
Search strains by all related name:
ispU b0174 ECK0173 JW0169 o253 orf18 rth uppS yaeS
|
General information (Go to Linear View: )
|
|
Gene Name
|
ispU
|
|
Alternative name
|
b0174,ECK0173,JW0169,o253,orf18,rth,uppS,yaeS
|
|
Location, Length
|
194,903 - 195,664
(
+
)
;
4.20
min
;
762
(bp) ,
253
(aa)
|
|
Product
|
undecaprenyl pyrophosphate synthase
|
|
Operon Name
|
ispU
|
|
Note
|
undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); GO_component: GO:0005737 - cytoplasm; GO_function: GO:0042280 - cell surface antigen activity, host-interacting
|
|
Function
|
|
|
Gene Ontology
|
GO:0007047
;
cell wall organization and biogenesis ( uppS )
GO:0007049
;
cell cycle ( uppS )
GO:0008152
;
metabolic process ( uppS )
GO:0008360
;
regulation of cell shape ( uppS )
GO:0008834
;
di-trans,poly-cis-decaprenylcistransferase activity ( uppS )
GO:0009252
;
peptidoglycan biosynthetic process ( uppS )
GO:0016740
;
transferase activity ( uppS )
GO:0051301
;
cell division ( uppS )
|
|
PID
|
1786371
|
EC number
(KEGG Pathway)
|
2.5.1.31
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
ispU
(
EG13329
)
|
|
Number of removed
|
1 aa cleaved
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
UPPS_ECOLI
(
P60472
;
P75668; Q47675; Q9R2E4
)
|
|
- Protein name
|
Undecaprenyl pyrophosphate synthetase
|
|
- Synonyms
|
EC 2.5.1.31, UPP synthetase, Di-trans-poly-cis-decaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS
|
|
- Gene name
|
Name=uppS; Synonyms=ispU, rth; OrderedLocusNames=b0174;
|
| Sequences |
Amino acid
FASTA format
|
0001 MMLSATQPLS EKLPAHGCRH VAIIMDGNGR WAKKQGKIRA FGHKAGAKSV RRAVSFAANN GIEALTLYAF
0071 SSENWNRPAQ EVSALMELFV WALDSEVKSL HRHNVRLRII GDTSRFNSRL QERIRKSEAL TAGNTGLTLN
0141 IAANYGGRWD IVQGVRQLAE KVQQGNLQPD QIDEEMLNQH VCMHELAPVD LVIRTGGEHR ISNFLLWQIA
0211 YAELYFTDVL WPDFDEQDFE GALNAFANRE RRFGGTEPGD ETA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GCTTTATAAG GTCAGATATG CCGTGGTTTT
-070 ACACGGCTTT TTTTTGTATA GGCTTCAGTA TTCCTGAGTA CCGTAAACCC TGTCAGGGAA TAAAAAACGC
0001 gtgatgttgt ctgctactca accacttagc gaaaaattgc cagcgcatgg ctgccgtcat gttgcgatca
0071 ttatggacgg caatggccgc tgggcaaaaa agcaagggaa gattcgtgcc tttgggcata aagccggggc
0141 aaaatccgtc cgccgggctg tctcttttgc ggccaacaac ggtattgagg cgttaacgct gtatgccttt
0211 agtagtgaaa actggaaccg accagcgcag gaagtcagtg cgttaatgga actgtttgtg tgggcgctcg
0281 atagcgaagt aaaaagtctg caccgacata acgtgcgtct gcgtattatt ggcgatacca gtcgctttaa
0351 ctcgcgtttg caagaacgta ttcgtaaatc tgaagcgcta acagccggga ataccggtct gacgctgaat
0421 attgcggcga actacggtgg acgttgggat atagtccagg gagtcaggca actggctgaa aaggtgcagc
0491 aaggaaacct gcaaccagat cagatagatg aagagatgct aaaccagcat gtctgtatgc atgaactggc
0561 ccctgtagat ttagtaatta ggactggggg ggagcatcgc attagtaact ttttgctttg gcaaattgcc
0631 tatgccgaac tttactttac agatgttctc tggcccgatt tcgatgaaca agactttgaa ggggcgttaa
0701 atgcctttgc taatcgagag cgtcgtttcg gcggcaccga gcccggtgat gaaacagcct gaTGGGGGTC
0771 GCTTTTGCTG AAGTATCGCC TGATATCTGC TTTTGTGTTA ATACCCGTCG TCATCGCGGC GTTGTTTCTG
0841 TTGCCGCCGG TGGGGTTCGC CA
|
