|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Mol Microbiol. 1991;5(7):1639-48.
The gef gene from Escherichia coli is regulated at the level of translation.
Poulsen LK, Refn A, Molin S, Andersson P.
(
1943701
)
|
|
|
Deletion
|
OCR27
(D)
,
OCR27-8
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
hokC
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
hokC
Search strains by all related name:
hokC b0018 b4412 ECK0018 f69 gef JW5879 mokC
|
General information (Go to Linear View: )
|
|
Gene Name
|
hokC
|
|
Alternative name
|
b0018,b4412,ECK0018,f69,gef,JW5879,mokC
|
|
Location, Length
|
16,751 - 16,903
(
-
)
;
0.36
min
;
153
(bp) ,
50
(aa)
|
|
Product
|
toxic membrane protein, small
|
|
Operon Name
|
mokC-hokC
|
|
Note
|
small toxic membrane polypeptide
|
|
Function
|
component of addiction module,cell killing
|
|
Gene Ontology
|
GO:0005886
;
plasma membrane ( hokC )
GO:0016020
;
membrane ( hokC )
GO:0016020
;
membrane ( mokC )
GO:0016021
;
integral to membrane ( hokC )
GO:0016021
;
integral to membrane ( mokC )
|
|
PID
|
48994874
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
HOKC_ECOLI
(
P22982
;
P75618
)
|
|
- Protein name
|
HokC protein
|
|
- Synonyms
|
Protein gef
|
|
- Gene name
|
Name=hokC; Synonyms=gef; OrderedLocusNames=b0018.1, SF0015.1, S0017;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
mokC
(
homologous genes of other bacterias
)
hokC
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Regulatory protein mokC
|
|
PSI-BLAST
|
Regulatory protein mokC
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
regulatory protein for HokC, overlaps CDS of hokC [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
HOK_GEF
|
|
MMBR References
|
Appl Environ Microbiol. 1993;59:3713-3717
A substrate-dependent biological containment system for Pseudomonas putida based on the Escherichia coli gef gene.
Jensen, L. B., J. L. Ramos, Z. Kaneva, and S. Molin.
|
Mol Microbiol. 1991;5(7):1639-48.
The gef gene from Escherichia coli is regulated at the level of translation.
Poulsen LK, Refn A, Molin S, Andersson P.
(
1943701
)
|
Mol Microbiol. 1991;5(7):1627-37.
Topographic analysis of the toxic Gef protein from Escherichia coli.
Poulsen LK, Refn A, Molin S, Andersson P.
(
1943700
)
|
Mol Microbiol. 1989;3(11):1463-72.
A family of genes encoding a cell-killing function may be conserved in all gram-negative bacteria.
Poulsen LK, Larsen NW, Molin S, Andersson P.
(
2693900
)
|
Mol Microbiol. 1992;6(7):895-905.
Analysis of an Escherichia coli mutant strain resistant to the cell-killing function encoded by the gef gene family.
Poulsen LK, Larsen NW, Molin S, Andersson P.
(
1602968
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MKQHKAMIVA LIVICITAVV AALVTRKDLC EVHIRTGQTE VAVFTAYESE
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 aaagccccga gtgatatttt accatcaacc
-070 cgaggcctcc tatatgctga acacatgtag agtgcctctt actgaccgta aggtcaagga gaagagagca
0001 atgaagcagc ataaggcgat gattgtcgcc ctgatcgtca tctgtatcac cgccgtagtg gcggcgctgg
0071 taacgagaaa agacctctgt gaggttcaca tccgaactgg ccagacggag gttgctgttt tcacggctta
0141 cgaatccgag taagagcaac ggcggggagt gatcccataa gcgctaactt aagggttgaa ccatctgaag
0211 aatgcgacgc ctcggtgcct cgttaagacg atgcctcgcg ttc
|
