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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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|
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Deletion
|
OCR28
(D)
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|
Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
dapB
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Related strains
|
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Strains Search
|
Search strains by gene name:
dapB
Search strains by all related name:
dapB b0031 ECK0032 JW0029
|
General information (Go to Linear View: )
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Gene Name
|
dapB
|
|
Alternative name
|
b0031,ECK0032,JW0029
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Location, Length
|
28,374 - 29,195
(
+
)
;
0.61
min
;
822
(bp) ,
273
(aa)
|
|
Product
|
dihydrodipicolinate reductase
|
|
Operon Name
|
dapB
|
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Note
|
GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0009089 - lysine biosynthetic process via diaminopimelate
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Function
|
enzyme; Amino acid biosynthesis: Lysine
|
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Gene Ontology
|
GO:0003824
;
catalytic activity ( dapB )
GO:0005488
;
binding ( dapB )
GO:0005737
;
cytoplasm ( dapB )
GO:0008152
;
metabolic process ( dapB )
GO:0008652
;
amino acid biosynthetic process ( dapB )
GO:0008839
;
dihydrodipicolinate reductase activity ( dapB )
GO:0009085
;
lysine biosynthetic process ( dapB )
GO:0009089
;
lysine biosynthetic process via diaminopimelate ( dapB )
GO:0016491
;
oxidoreductase activity ( dapB )
GO:0019877
;
diaminopimelate biosynthetic process ( dapB )
|
|
PID
|
1786214
|
EC number
(KEGG Pathway)
|
1.3.1.26
|
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SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
DAPB_ECOLI
(
P04036
)
|
|
- Protein name
|
Dihydrodipicolinate reductase
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- Synonyms
|
EC 1.3.1.26, DHPR
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- Gene name
|
Name=dapB; OrderedLocusNames=b0031;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
|
dapB
(
homologous genes of other bacterias
)
|
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PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain , Mol_id: 1; Molecule: Dihydrodipicolinate Reductase; Chain: Null; Ec: 1.3.1.26; Engineered: Yes
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
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BLAST
|
Dihydrodipicolinate reductase
|
|
PSI-BLAST
|
Dihydrodipicolinate reductase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
dihydrodipicolinate reductase [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
|
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PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
DAPB
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MMBR References
|
J Biol Chem. 1980;255:8928-8935
Cloning of fragments of lambda dapB2 DNA and identification of the dapB gene product.
Mackie, G. A.
|
J Biol Chem. 1984;259:14829-14834
Nucleotide sequence and expression of the Escherichia coli dapB gene.
Bouvier, J., F. Richaud, C. Richaud, J. C. Patte, and P. Stragier.
|
| Sequences |
Amino acid
FASTA format
|
0001 MHDANIRVAI AGAGGRMGRQ LIQAALALEG VQLGAALERE GSSLLGSDAG ELAGAGKTGV TVQSSLDAVK
0071 DDFDVFIDFT RPEGTLNHLA FCRQHGKGMV IGTTGFDEAG KQAIRDAAAD IAIVFAANFS VGVNVMLKLL
0141 EKAAKVMGDY TDIEIIEAHH RHKVDAPSGT ALAMGEAIAH ALDKDLKDCA VYSREGHTGE RVPGTIGFAT
0211 VRAGDIVGEH TAMFADIGER LEITHKASSR MTFANGAVRS ALWLSGKESG LFDMRDVLDL NNL
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TTATCATTAA TTTCTAATTA TCAGCGTTTT
-070 TGGCTGGCGG CGTAGCGATG CGCTGGTTAC TCTGAAAACG GTCTATGCAA ATTAACAAAA GAGAATAGCT
0001 atgcatgatg caaacatccg cgttgccatc gcgggagccg gggggcgtat gggccgccag ttgattcagg
0071 cggcgctggc attagagggc gtgcagttgg gcgctgcgct ggagcgtgaa ggatcttctt tactgggcag
0141 cgacgccggt gagctggccg gagccgggaa aacaggcgtt accgtgcaaa gcagcctcga tgcggtaaaa
0211 gatgattttg atgtgtttat cgattttacc cgtccggaag gtacgctgaa ccatctcgct ttttgtcgcc
0281 agcatggcaa agggatggtg atcggcacta cggggtttga cgaagccggt aaacaagcaa ttcgtgacgc
0351 cgctgccgat attgcgattg tctttgctgc caattttagc gttggcgtta acgtcatgct taagctgctg
0421 gagaaagcag ccaaagtgat gggtgactac accgatatcg aaattattga agcacatcat agacataaag
0491 ttgatgcgcc gtcaggcacc gcactggcaa tgggagaggc gatcgcccac gcccttgata aagatctgaa
0561 agattgcgcg gtctacagtc gtgaaggcca caccggtgaa cgtgtgcctg gcaccattgg ttttgccacc
0631 gtgcgtgcag gtgacatcgt tggtgaacat accgcgatgt ttgccgatat tggcgagcgt ctggagatca
0701 cccataaggc gtccagccgt atgacatttg ctaacggcgc ggtaagatcg gctttgtggt tgagtggtaa
0771 ggaaagcggt ctttttgata tgcgagatgt acttgatctc aataatttgt aaCCACAAAA TATTTGTTAT
0841 GGTGCAAAAA TAACACATTT AATTTATTGA TTATAAAGGG CTTTAATTTT TGGCCCTTTT ATTTTTGGTG
0911 TTATGTTTTT AA
|
