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PEC Original Annotations
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Essentiality
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Class
|
non-essential
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|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
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Deletion
|
OCR28
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
caiT
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
caiT
Search strains by all related name:
caiT b0040 ECK0041 JW0039 yaaP
|
General information (Go to Linear View: )
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|
Gene Name
|
caiT
|
|
Alternative name
|
b0040,ECK0041,JW0039,yaaP
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|
Location, Length
|
40,417 - 41,931
(
-
)
;
0.87
min
;
1515
(bp) ,
504
(aa)
|
|
Product
|
putative transporter
|
|
Operon Name
|
caiTABCDE
|
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Note
|
probable carnitine transporter; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0016052 - carbohydrate catabolic process
|
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Function
|
putative transport; Central intermediary metabolism: Pool, multipurpose conversions
|
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Gene Ontology
|
GO:0005215
;
transporter activity ( caiT )
GO:0005886
;
plasma membrane ( caiT )
GO:0006810
;
transport ( caiT )
GO:0015297
;
antiporter activity ( caiT )
GO:0016020
;
membrane ( caiT )
GO:0016021
;
integral to membrane ( caiT )
|
|
PID
|
1786224
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
CAIT_ECOLI
(
P31553
;
P75624
)
|
|
- Protein name
|
L-carnitine/gamma-butyrobetaine antiporter.
|
|
- Synonyms
|
|
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- Gene name
|
Name=caiT; OrderedLocusNames=b0040;
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Homology Analysis
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BLAST
|
|
Bacteria
|
|
GTOP
|
caiT
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
L-carnitine/gamma-butyrobetaine antiporter
|
|
PSI-BLAST
|
L-carnitine/gamma-butyrobetaine antiporter
|
|
nr
(database updated :
2007.02.20
)
|
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BLAST
|
L-carnitine/gamma-butyrobetaine antiporter [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
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Pfam
|
|
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PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
PROKAR_LIPOPROTEIN
BCCT
|
|
MMBR References
|
Mol Microbiol. 1994;13(5):775-86.
Molecular characterization of the cai operon necessary for carnitine metabolism in Escherichia coli.
Eichler K, Bourgis F, Buchet A, Kleber HP, Mandrand-Berthelot MA.
(
7815937
)
|
J Bacteriol. 1998;180:2599-2608
Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region.
Buchet, A., K. Eichler, and M. A. Mandrand-Berthelot.
|
| Sequences |
Amino acid
FASTA format
|
0001 MKNEKRKTGI EPKVFFPPLI IVGILCWLTV RDLDAANVVI NAVFSYVTNV WGWAFEWYMV VMLFGWFWLV
0071 FGPYAKKRLG NEPPEFSTAS WIFMMFASCT SAAVLFWGSI EIYYYISTPP FGLEPNSTGA KELGLAYSLF
0141 HWGPLPWATY SFLSVAFAYF FFVRKMEVIR PSSTLVPLVG EKHAKGLFGT IVDNFYLVAL IFAMGTSLGL
0211 ATPLVTECMQ WLFGIPHTLQ LDAIIITCWI ILNAICVACG LQKGVRIASD VRSYLSFLML GWVFIVSGAS
0281 FIMNYFTDSV GMLLMYLPRM LFYTDPIAKG GFPQGWTVFY WAWWVIYAIQ MSIFLARISR GRTVRELCFG
0351 MVLGLTASTW ILWTVLGSNT LLLIDKNIIN IPNLIEQYGV ARAIIETWAA LPLSTATMWG FFILCFIATV
0421 TLVNACSYTL AMSTCREVRD GEEPPLLVRI GWSILVGIIG IVLLALGGLK PIQTAIIAGG CPLFFVNIMV
0491 TLSFIKDAKQ NWKD
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 aacgcgtcca cgaggttaat aataattata
-070 ttaaatgtta acaaaaataa aacaaacggg aacgcaaaat aaatattcgt tttcacagtg gaattaactc
0001 atgaagaatg aaaagagaaa aacgggaata gaaccgaagg ttttctttcc gccgttaata atcgtcggca
0071 tactttgttg gcttacagtc agagatctgg atgcagcgaa tgtcgttatt aatgctgtat tcagttacgt
0141 caccaatgta tggggatggg catttgaatg gtatatggtg gtgatgcttt tcggttggtt ctggctggtg
0211 tttggcccgt atgccaaaaa gcgtttaggt aacgaaccgc cagaatttag caccgccagt tggatcttta
0281 tgatgttcgc ctcctgtacg tctgctgccg tactgttctg gggatcgatt gagatctact actacatctc
0351 caccccgccg tttggcttag aaccgaactc gacaggggcg aaagagttgg ggctggctta cagcttgttc
0421 cactggggac ctctgccgtg ggccacttac agcttccttt cagtcgcctt cgcttacttc ttctttgtcc
0491 gcaaaatgga agtgattcgc cccagctcga cactggtgcc gctggtaggt gaaaaacacg ccaaagggtt
0561 gttcggcact atcgtcgaca acttctatct cgtcgccttg atcttcgcga tgggtaccag tctgggcctt
0631 gccacgccgc tggtgaccga gtgtatgcaa tggttgtttg gcattccgca taccctgcaa ctggacgcta
0701 tcatcattac ctgctggatt atcctcaacg ccatttgcgt cgcttgcggt ctgcaaaaag gggtacgtat
0771 cgccagtgac gtgcgtagtt acctgagctt cctgatgctg ggttgggtgt tcattgtcag cggtgccagc
0841 ttcatcatga actacttcac cgattcggtg gggatgttgc tgatgtatct gccgcgcatg ttgttctata
0911 ccgatcccat cgctaaaggc ggcttcccgc agggctggac cgtgttctac tgggcatggt gggtgattta
0981 tgctatccag atgagtatct tcctcgcccg catctcccgt ggtcgtactg tgcgtgaact gtgcttcggc
1051 atggtgctgg ggctgacagc gtcaacctgg atcctgtgga ctgtactcgg tagtaacact ctgctgttga
1121 tagataaaaa catcatcaac attccaaatc tgatcgaaca gtacggtgtg gcgcgcgcca tcattgaaac
1191 ctgggccgct ctgccactca gcaccgccac catgtggggc ttcttcatcc tctgctttat tgccaccgtt
1261 acgctggtta acgcctgctc ttataccctg gcgatgtcca cttgccgcga agtacgcgat ggtgaagaac
1331 cacctctgct ggtgcgtatc ggttggtcaa ttctggttgg cattatcggt attgttctgc tggcgctcgg
1401 cggcctgaaa ccgattcaaa ccgccattat cgccggagga tgcccgctgt tcttcgtcaa cattatggtg
1471 acgctctcct ttattaaaga cgcgaaacag aactggaaag attaattaac ccccaaaata tcaagaggtt
1541 gaaagatgga ttttaattta aatgatgagc aggaactgtt tgtcgccggt atccgcgaac tgatggccag
1611 cgaaa
|
