MG1655
W3110
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Gene Report : fixC
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Basic Microbiol. 1995;35(4):217-27.
The fix Escherichia coli region contains four genes related to carnitine metabolism.
Eichler K, Buchet A, Bourgis F, Kleber HP, Mandrand-Berthelot MA. ( 7473063 )
     Deletion OCR28 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  fixC
Related strains
     Strains Search Search strains by gene name:  fixC   Search strains by all related name:  fixC b0043 ECK0044 JW0042 yaaS

General information  (Go to Linear View:)
 Gene Name fixC  
 Alternative name b0043,ECK0044,JW0042,yaaS  
 Location, Length 44,180 - 45,466 (  +  ) ;   0.95 min ; 1287 (bp) ,   428 (aa) Go to Linear View
 Product putative oxidoreductase with FAD/NAD(P)-binding domain  
 Operon Name fixABCX  
 Note flavoprotein; electron transport; GO_process: GO:0042413 - carnitine catabolic process  
 Function putative carrier; Energy metabolism, carbon: Electron transport  
 Gene Ontology GO:0006118 ; electron transport ( fixC )
GO:0006810 ; transport ( fixC )
GO:0008152 ; metabolic process ( fixC )
GO:0016491 ; oxidoreductase activity ( fixC )
 PID 1786227  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) FIXC_ECOLI ( P31575 ; P75626 )
    -  Protein name FixC protein.  
    -  Synonyms  
    -  Gene name Name=fixC; OrderedLocusNames=b0043, c0053;  

 Linear View (Whole Mode)
View Location
   35.0  –  60.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP fixC (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Structure Of Porcine Electron Transfer Flavoprotein- Ubiquinone Oxidoreductase In Complexed With Ubiquinone  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Protein fixC  
         PSI-BLAST tRNA uridine 5-carboxymethylaminomethyl modification enzyme gidA
    nr     (database updated : 2007.02.20 )
         BLAST predicted oxidoreductase with FAD/NAD(P)-binding domain [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    AMIDATION     

Other Cross-Reference
    COG COG0644C 
    EcoCyc fixC 

MMBR References
J Basic Microbiol. 1995;35(4):217-27.
The fix Escherichia coli region contains four genes related to carnitine metabolism.
Eichler K, Buchet A, Bourgis F, Kleber HP, Mandrand-Berthelot MA. ( 7473063 )
J Bacteriol. 1998;180:2599-2608
Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region.
Buchet, A., K. Eichler, and M. A. Mandrand-Berthelot.

Sequences
Amino acid
FASTA format 
0001 MSEDIFDAII VGAGLAGSVA ALVLAREGAQ VLVIERGNSA GAKNVTGGRL YAHSLEHIIP GFADSAPVER 
0071 LITHEKLAFM TEKSAMTMDY CNGDETSPSQ RSYSVLRSKF DAWLMEQAEE AGAQLITGIR VDNLVQRDGK 
0141 VVGVEADGDV IEAKTVILAD GVNSILAEKL GMAKRVKPTD VAVGVKELIE LPKSVIEDRF QLQGNQGAAC 
0211 LFAGSPTDGL MGGGFLYTNE NTLSLGLVCG LHHLHDAKKS VPQMLEDFKQ HPAVAPLIAG GKLVEYSAHV 
0281 VPEAGINMLP ELVGDGVLIA GDAAGMCMNL GFTIRGMDLA IAAGEAAAKT VLSAMKSDDF SKQKLAEYRQ 
0351 HLESGPLRDM RMYQKLPAFL DNPRMFSGYP ELAVGVARDL FTIDGSAPEL MRKKILRHGK KVGFINLIKD 
0421 GMKGVTVL
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             GCGACGCCGT GAAGATCCTT CCGGCGCTGA 
-070 CCGCAGCTTT AGCGCGTTGA TCCACTCTGG CAGGGCTGCA TTTTGGCCCT GCCGCTGACA GGGAGCTCTT 
0001 atgtccgaag atatctttga cgccatcatc gtcggtgcag ggcttgccgg ttcggttgcc gcactggtgc 
0071 tcgcccgcga aggtgcgcaa gtgttagtta tcgagcgtgg caattccgca ggtgccaaga acgtcaccgg 
0141 cgggcgtctc tatgcccaca gtctggaaca cattattcct ggtttcgccg actccgcccc cgtagaacgc 
0211 ctgatcaccc atgaaaaact cgcgtttatg acggaaaagt cagcgatgac tatggactac tgcaatggtg 
0281 acgaaacctc gccatcccag cgttcttact ccgttttgcg cagtaaattt gatgcctggc tgatggagca 
0351 ggccgaagaa gcgggcgcgc agttaattac cgggatccgc gtcgataacc tcgtacagcg cgatggcaaa 
0421 gtcgtcggtg tagaagccga tggcgatgtg attgaagcga aaacggtgat ccttgctgat ggggtgaact 
0491 ccatccttgc cgaaaaattg gggatggcaa aacgcgtcaa accgacggat gtggcggttg gcgtgaagga 
0561 actgatcgag ttaccgaagt cggttattga agaccgtttt cagttgcagg gtaatcaggg ggcggcttgc 
0631 ctgtttgcgg gatcacccac cgatggcctg atgggcggcg gcttccttta taccaatgaa aacaccctgt 
0701 cgctggggct ggtttgtggt ttgcatcatc tgcatgacgc gaaaaaatcg gtgccgcaaa tgctggaaga 
0771 tttcaaacag catccggccg ttgcaccgct gatcgcgggc ggcaagctgg tggaatattc cgctcacgta 
0841 gtgccggaag caggcatcaa catgctgccg gagttggttg gtgacggcgt attgattgcc ggtgatgccg 
0911 ccggaatgtg tatgaacctc ggttttacca ttcgcggtat ggatctggcg attgccgccg gggaagccgc 
0981 agcaaaaacc gtgctttcag cgatgaaaag cgacgatttc agtaagcaaa aactggcgga atatcgtcag 
1051 catcttgaga gtggtccgct gcgcgatatg cgtatgtacc agaaactacc ggcgttcctt gataacccac 
1121 gcatgtttag cggctacccg gagctggcgg tgggtgtggc gcgtgacctg ttcaccattg atggcagcgc 
1191 gccggaactg atgcgcaaga aaatcctccg ccacggcaag aaagtgggct tcatcaatct aatcaaggat 
1261 ggcatgaaag gagtgaccgt tttatgaCTT CTCCCGTCAA TGTGGACGTC AAACTGGGCG TCAATAAATT 
1331 CAATGTCGAT GAAGAGCATC CGCACATTGT TGTGAAGGCC GATGCTGATA AACAGGC